Triphenyl phosphite-mediated green synthesis of novel carboxycoumarin amides.
P. K. Sharma, D. Mathur, S. Malhotra, N. Rana, B. K. Singh,A. K. Prasad, A. J. Varma, N.A. Shakil, B. Ghosh, C. Len, R. C. Kuhad, F. Jerome, V. S. Parmar.
Curr. Green Chem. 2016, 3, 366-373.
Selective pinacol-coupling reaction using a continuous flow system.
N. Sotto, C. Cazorla, C. Villette, M. Billamboz, C. Len.
J. Org. Chem. 2016, 81, 11065-11071.
Toward the sustainable synthesis of biosourced divinylglycol from glycerol.
N. Sotto, C. Cazorla, C. Villette, M. Billamboz, C. Len.
ACS Sustainable Chem. Eng. 2016, 4, 6996-7003.
Synthesis of macromolecular systems via lipase catalyzed biocatalytic reactions: Applications and future perspectives.
A. Kumar,A. Khan,S. Malhotra,R. Mosurkal,A. Dhawan,M.K. Pandey, B.K. Singh,R. Kumar,A.K. Prasad, S.K. Sharma,L.A. Samuelson,A.L. Cholli, C. Len,N.G.J. Richards, J. Kumar,R. Haag, A.C. Watterson,V.S. Parmar.
Chem. Soc. Rev. 2016, 45, 6855-6887.
Glycerol in sub- and supercritical solvents.
N. Galy, R. Nguyen, H. Yalgin, N. Thiebault, D. Luart, C. Len.
J. Chem. Technol. Biotechnol. 2017, 92, 14-26.
Biocatalytic synthesis of novel partial esters of a bioactive dihydroxy 4-methylcoumarin by Rhizopus oryzae lipase (ROL).
V. Kumar, D. Mathur, Srivastava, S. Malhotra, N. Rana, S.K. Singh, B.K. Singh, A.K. Prasad, A.K. Varma, C Len, R. C. Kuhad, R.K. Saxena, V.S. Parmar.
Molecules 2016, 21, 1499-1509.
Furfural production from D-xylose and xylan by using stable Nafion NR50 and NaCl in a microwave-assisted biphasic reaction.
S. Le Guenic, D. Gergela, C. Ceballos, F. Delbecq, C. Len.
Molecules 2016, 21, 1102-1112.
Chemo-enzymatic synthesis of oligoglycerol derivatives.
A.K. Singh, R. Nguyen, N. Galy, R. Haag, S.K. Sharma, C. Len.
Molecules 2016, 21, 1038-1049.
Neuroprotective and antioxidant activities of 4-methylcoumarins: Development of structure-activity relationships.
S. Malhotra, M. Tavakkoli, N. Edraki, R. Miri, S.K. Sharma, A.K. Prasad, L. Saso, C. Len, V.S. Parmar and O. Firuzi.
Biol. Pharm. Bull. 2016, 39, 1544-1548.
Conversion of xylose, xylan and rice husk into furfural via betaine and formic acid mixture as novel homogeneous catalyst in biphasic system by microwave-assisted dehydration.
F. Delbecq, Y. Wang, C. Len.
J. Mol. Catal. A: Chemical 2016, 423, 520-525.
Conjugated dienyl derivatives by green bisallylic substitution : synthetic and mechanistic insight.
C. Cazorla, M. Billamboz, C. Chevrin-Villette, F. Hapiot, E. Monflier, C. Len.
ChemCatChem 2016, 8, 2321-2328.
Barton decarboxylation under ultrasonic continuous flow.
E. Banaszak-Leonard, F. Mangin, C. Len.
New J. Chem. 2016, 40, 7414-7420.
Modified fluorapatite as highly efficient catalyst for the synthesis of chalcones via Claisen-Schmidt condensation reaction.
I. Jioui, K. Danoun, A. Solhy, M. Jouiad, M. Zahouily, B. Essaid, C. Len, A. Fihri.
J. Ind. Eng. Chem. 2016, 39, 218-225.
Natural phosphate-supported palladium for hydration of aromatic nitriles to amides in aqueous medium.
A. Hassine, S. Sebti, A. Solhy, N. Thiebault, B. Essaid, C. Len, A. Fihri.
Curr. Org. Chem. 2016, 20, 2022-2028.
Microwave assisted metal free, base mediated C-N bond formation/cleavage : synthesis of benzimidazo[1,2-a]quinazoline derivatives.
P. Kumar, A.K. Singh, V. Bahadur, C. Len, N.G.J. Richards, V.S. Parmar, E. Van Der Eycken, B.K. Singh.
ACS Sustainable Chem. Eng. 2016, 4, 2206-2210.
Synthesis and anti-inflammatory activity evaluation of novel triazolyl-isatin hybrids.
P.K. Sharma, S.Balwani, D. Mathur, S. Malhotra, B.K. Singh, A.K. Prasad, C. Len, E.V. Van der Eycken, B. Ghosh, V.S. Parmar.
J. Enz. Inhib. Med. Chem. 2016, 31, 1520-1526.
First examples of Doebner-Miller reaction in flow: Efficient production of 2-methylquinoline derivatives in water.
H. Yalgin, D. Luart, C. Len.
J. Flow Chem. 2016, 6, 80-85.
Azobenzenes and catalysis.
E. Leonard, F. Mangin, C. Villette, M. Billamboz, C. Len.
Catal. Sci. Technol. 2016, 6, 379-398.
Simple green dehydration in water : Application to the synthesis of phenylacetaldehyde.
S. Le Guenic, C. Ceballos, C. Len.
J. Mol. Catal. A: Chemical 2016, 411, 72-77.
Comparison of direct and staged pyrolysis of the ligno-cellulosic biomass with the aim of the production of high added value.
I. Ouarzki, M. Hazi, D. Luart, C. Len, A. Ould-Driss.
J. Mater. Environ. Sci. 2016, 7, 1008-1022.
2015
Antifungal activity of synthesized dithiocarbamate derivatives on Fusarium oxysporum f sp. Albedinis in Algeria.
M. Loth, B. Meddah, A. Tir Touil, C. Len, W. Verstraete.
J. Chem. Pharm. Res. 2015, 7, 49-54.
Microwave-aided dehydration of D-xylose into furfural by diluted inorganic salts solution in a biphasic system.
S. Le Guenic, F. Delbecq, C. Ceballos, C. Len.
J. Mol. Catal. A: Chemical 2015, 410, 1-7.
Nano-structured pyrophosphate Na 2 CaP 2 O 7 as catalyst for selective synthesis of 1,2-disubstituted benzimidazoles in pure water.
K. Danoun, I. Jioui, M. Bouhrara, M. Zahouily, A. Solhy, M. Jouiad, C. Len, A. Fihri.
Curr. Org. Chem. 2015, 19, 2132-2140.
One-step Barton decarboxylation by micellar catalysis – application to the synthesis of maleimide derivatives.
F. Mangin, E. Banaszak-Léonard, C. Len.
RSC Adv. 2015, 5, 69616-69620.
Synthesis of phenylacetaldehyde from 1-phenylethan-1,2-diol by microwave-assisted dehydration in water.
S. Le Guenic, C. Ceballos, C. Len.
Catal. Letters 2015, 145, 1851-1855.
Selective pinacol coupling on regenerable supported acids in sole water.
N. Sotto, M. Billamboz, C. Chevrin-Villette, C. Len.
J. Org. Chem. 2015, 80, 6375-6380.
Simple and expeditious pinacol coupling of non usual a,b-unsaturated carbonyl compounds in water.
M. Billamboz, N. Sotto, C. Chevrin-Villette, C. Len.
RSC Adv. 2015, 5, 46026-46030.
Self-assembly, photoresponsible behavior and transport potential of azobenzene grafted dendronized polymeric amphiphiles.
M. Kumari, M. Billamboz, E. Leonard, C. Len, C. Böttcher, A.K. Prasad, R. Haag, S.K. Sharma.
RSC Adv. 2015, 5, 48301-48310.
Microwaves under pressure for the continuous production of quinoline from glycerol.
H. Saggadi, I. Polaert, D. Luart, C. Len, L. Estel.
Catalysis Today 2015, 255, 66-74.
Aqueous microwaves assisted cross-coupling reactions applied to unprotected nucleosides.
G. Herve, C. Len.
Front. Chem. 2015, 3, 10-12.
Synthesis of C -arylnucleoside analogues.
C. Len, G. Enderlin.
Molecules 2015, 20, 4967-4997.
First pinacol coupling in emulsified water: key role of surfactant and impact of alternative activation technologies.
M. Billamboz, C. Len.
ChemSusChem 2015, 8, 1664-1675.
Highly selective biocatalytic transesterification reactions on aryl 3-hydroxy-2-(hydroxymethyl)-2-methylpropanoates.
G. Kumar, A. Dhawan, B.K. Singh, N.K. Sharma, S.K. Sharma, A.K. Prasad, E.V. Van Der Eycken, C. Len, A.C. Watterson, V.S. Parmar.
Catal. Lett. 2015, 145, 919-929.
Coupling of OECD standardized test and immunomarlers to select the most environmentally benign ionic liquid option – Towards an innovative “safety by design” approach.
A. Bado-Nilles, A.O. Diallo, G. Marlair, P. Pandard, L. Chabot, A. Geffard, C. Len, J.M. Porcher, W. Sanchez.
J. Hazard. Mater. 2015, 283, 202-210.
2014
Natural phosphate-supported palladium: a highly efficient and recyclable catalyst for the Suzuki-Miyaura coupling under microwave irradiation.
A. Hassine, M. Bouhrara, S. Sebti, A. Solhy, D. Luart, C. Len, A. Fihri.
Curr. Org. Chem. 2014, 18, 3141-3148.
Original access to 5-aryluracils from 5-iodo-2'-deoxyuridine via a microwave assisted Suzuki-Miyaura cross-coupling/deglycosydation sequence in pure water.
T. Lussier, G. Herve, G. Enderlin, C. Len.
RSC Adv. 2014, 4, 46218-46223.
First ligand-free microwaves-assisted Heck cross-coupling reaction in sole water on nucleoside – Application to the synthesis of antiviral BVDU.
G. Herve, C. Len.
RSC Adv. 2014, 4, 46926-46929.
Synthesis and characterization of a new photo-induced switchable b -cyclodextrin dimer.
F. Hamon, C. Blaszkiewicz, M. Buchotte, E. Banaszak-Léonard, H. Bricout, S. Tilloy, E. Monflier, C. Cezard, L. Bouteiller, C. Len, F. Djedaini-Pilard.
Beilstein J. Org. Chem. 2014, 10, 2874-2885.
Ceria-supported copper nanoparticles: A highly efficient and recyclable catalyst for N-arylation of indole.
O. Amadine, H. Maati, K. Abdelouhadi, A. Fihri, S. El Kazzouli, C. Len, A. El Bouari, A. Solhy.
J. Mol. Catal. A: Chemical 2014, 395, 409-419.
Solventless oxidative coupling of amines to imines by using transition-metal-free metal-organic frameworks.
X. Qiu, C. Len, R. Luque, Y. Li.
ChemSusChem 2014, 7, 1684-1688.
Quinoline and phenanthroline preparation starting from glycerol via improved microwave-assisted modified Skraup reaction.
H. Saggadi, D. Luart, N. Thiebault, I. Polaert, L. Estel, C. Len.
RSC Adv. 2014, 4, 21456-21464.
Palladium-catalyzed Suzuki reaction in aqueous solvents applied to unprotected nucleosides and nucleotides.
G. Herve, G. Sartori, G. Enderlin, G. Mackenzie, C. Len.
RSC Adv. 2014, 4, 18558-18594.
High-affinity RNA targeting by oligonucleotides displaying aromatic stacking and amino groups in the major groove. Comparison of triazoles and phenyl substituents.
P. Kumar, M. Hornum, L.J. Nielsen, G. Enderlin, N.K. Andersen, C. Len, G. Herve, G. Sartori, P. Nielsen.
J. Org. Chem. 2014, 79, 2854-2863.
Continuous flow transformations of glycerol to valuable products: an overview.
C. Len, R. Luque.
Sustainable Chem. Process. 2014, 2, 1-10.
Targeting adequate thermal stability and fire safety in selecting ionic liquid-based electrolytes for energy storage.
L. Chancelier, A.O. Diallo, C.C. Santini, G. Marlair, T. Gutel, S. Mailley, C. Len.
Phys. Chem. Chem. Phys. 2014, 16, 1967-1976. Hot article 16 dec 2013
Micellar catalysis using a photochromic surfactant : application to the Pd-catalysed Tsuji-Trost reaction in water.
M. Billamboz, F. Mangin, E. Banaszak-Leonard, C. Chevrin Villette, N. Drillaud, C. Len.
J. Org. Chem. 2014, 79, 493-500.
Toward the synthesis of 6-hydroxyquinoline starting from glycerol via improved microwave-assisted modified Skraup reaction.
H. Saggadi, D. Luart, N. Thiebault, I. Polaert, L. Estel, C. Len.
Catal. Commun. 2014, 44, 15-18.
2013
Developing dedicated methods and tools for safe use and processing of key chemicals in biorefining.
G. Marlair, A.O. Diallo, W. Benaissa, A. Vignes, L. Blanc, C. Len.
Chem. Eng. Trans. 2013, 31, 859-864.
A cyclodextrin dimer as supramolecular reaction platform for aqueous organometallic catalysis.
C. Blaszkiewicz, H. Bricout, E. Leonard, C. Len, D. Landy, F. Djedaini-Pilard, E. Monflier, S. Tilloy.
Chem. Commun. 2013, 49, 6989-6991.
Synthesis of 6-aryluridines via Suzuki-Miyaura cross-coupling reaction at room temperature under aerobic ligand-free conditions in neat water.
G. Enderlin, G. Sartori, G. Herve, C. Len.
Tetrahedron Lett. 2013, 54, 3374-3377.
Improved microwave-assisted ligand-free Suzuki-Miyaura cross-coupling of 5-iodo-2'-deoxyuridine in pure water.
S. Gallagher-Duval, G. Herve, G. Sartori, G. Enderlin, C. Len.
New J. Chem. 2013, 37, 1989-1995.
b -Cyclodextrin-glycerol dimmers: their synthesis and NMR conformational analysis.
V. Legros, C. Vanhaverbecke, F. Souard, C. Len, J. Desire.
Eur. J. Org. Chem. 2013, 2583-2590.
An innovative experimental approach aiming to understand and quantifiy the acual fire hazards of ionic liquids.
A.O Diallo, A.B. Morgan, C. Len, G. Marlair.
Energy Environ. Sci. 2013, 6, 699-710.
Ligandless Suzuki-Miyaura reaction in neat water with or without native b -cyclodextrin as additive.
A. Decottignies, A. Fihri, G. Azemar, F. Djedaini-Pilard, C. Len.
Catal. Commun. 2013, 32, 101-107.
New efficient approach of ligand-free Suzuki-Miyaura reaction applied to 5-iodo-2'-deoxyuridine in neat water.
G. Sartori, G. Enderlin, G. Herve, C. Len.
Synthesis 2013, 45, 330-333.
Palladium Supported on Natural Phosphate: Catalyst for Suzuki Coupling Reactions in Water.
A. Hassine, S. Sebti, A Solhy, M. Zahouily, C. Len, M.N. Hedhili, A. Fihri.
Applied Catalysis A: General 2013, 450, 13-18.
2012
Development of new triazolyl-based acidic sensitive releasing systems.
R. Delatouche, M. Mondon, F. Collette, C. Bachmann, G. Frapper, C. Len, V. Heroguez, P. Bertrand.
Latvian J. Chem. 2012, 1/2, 41-48.
Synthesis and evaluation of photochromic surfactant for organic reactions in aqueous media.
N. Drillaud, E. Banaszac-Leonard, I. Pezron, C. Len.
J. Org. Chem. 2012, 77, 9553-9561.
Water-soluble diphosphadiazacyclooctanes as ligands for aqueous organometallic catalysis.
J. Boulanger, H. Bricout, S. Tilloy, A. Fihri, C. Len, F. Hapiot, E. Monflier.
Catal. Commun. 2012, 29, 77-81.
Impact of cyclodextrins on the behavior of amphiphilic ligands in aqueous organometallic catalysis.
H. Bricout, E. Leonard, C. Len, D. Landy, F. Hapiot, E. Monflier.
Beilstein J. Org. Chem. 2012, 8, 1479-1484.
Revisiting phys.-chem. Related safety issues of ionic liquids.
A.O Diallo, C. Len, A.B. Morgan, G. Marlair.
Sep. Purif. Technol. 2012, 97, 228-234.
Evaluation of heats of combustion of ionic liquids through use of existing and purpose built models.
A.O Diallo, G. Fayet, C. Len, G. Marlair.
Ind. Eng. Chem. Res. 2012, 51, 3149-3156.
Highly effective synthesis of C-5-substituted 2'-deoxyuridine using Suzuki-Miyaura cross-coupling in water.
G. Sartori, G. Enderlin, G. Herve, C. Len.
Synthesis 2012, 44, 767-772.
Formal synthesis of TMC 69-6H via a one-pot enantioselective proline-mediated aldol/olefin homologation procedure.
S. Vuong, N. Brondel, C. Len, S. Papot, B. Renoux.
Tetrahedron 2012, 68, 433-439.
Novel strategy for the bis-butenolide synthesis via ring closing metathesis.
M. Billamboz, J.C. Legeay, F. Hapiot, E. Monflier, C. Len.
Synthesis 2012, 44, 137-143.
2011
Synthesis and Biological Evaluation of 4'-C ,3'-O-Propylene-Linked Bicyclic Nucleosides.
W. Hatton, J. Hunault, M. Egorov, C. Len, M. Pipelier, V. Blot, V. Silvestre, V. Fargeas, A. Ane, T. McBrayer, M. Detorio, J.H. Cho, N. Bourgougnon, D. Dubreuil, R.F. Schinazi, J. Lebreton S
Eur. J. Org. Chem. 2011, 7390-7399.
Selectivity in C-alkylation of dianions of protected 6-methyluridine.
N.H. Nguyen, C. Len, A.S. Castanet, J. Mortier.
Beilstein J. Org. Chem. 2011, 7 1228-1233.
Regioselective functionalization of glycerol with a dithiocarbamate moiety: an environmentally friendly route to safer fungicides.
R. DeSousa, C. Thurier, C. Len, Y. Pouilloux, J. Barrault, F. Jerome.
Green Chem. 2011, 13, 1129-1132.
Triazolyl Derivatives for acidic release of alcohols.
M. Mondon, R. Delatouche, C. Bachmann, G. Frapper, C. Len, P. Bertrand.
Eur. J. Org. Chem. 2011, 2111-2119.
Suzuki-Miyaura cross-coupling reactions with low catalyst loading: a green and sustainable protocol in pure water.
A. Fihri, D. Luart, C. Len, A. Solhy, C. Chevrin, V. Polshettiwar.
Dalton Transactions 2011, 40, 3116-3121.
Toward the supramolecular cyclodextrin dimers using nucleobase pairs.
V. Legros, F. Hamon, B. Violeau, F. Turpin, F. Djedaini-Pilard, J. Désiré, C. Len.
Synthesis 2011, 2, 235-242.
2010
Synthesis of a novel uridine and its use in attemps to form new cyclonucleosides using ring-closing metathesis.
S. Zhong, M. Mondon, C. Len.
Sc. China Chem. 2010, 53, 1932-1936.
Amphiphilic photo-isomerisable phosphanes for aqueous organometallic catalysis.
H. Bricout, E. Banaszak, C. Len, F. Hapiot, E. Monflier.
Chem. Commun. 2010, 46, 7813-7815.
Synthesis of bicyclonucleosides having a C-C bridge.
C. Lebreton, J.M. Escudier, L. Arzel, C. Len.
Chem. Rev. 2010, 110, 3371-3418.
Suzuki-Miyaura cross-coupling in aqueous media: green and sustainable syntheses of biaryl (pNA).
V. Polshettiwar, A. Decottignies, C. Len, A. Fihri.
ChemSusChem. 2010, 5, 502-522.
Diol appended quenchers for fluorescein boronic acid.
S. A. Elfeky, S.E. Flower, N. Masumoto, F. D'Hooge, L. Labarthe, W. Chen, C. Len, T.D. James, J.S. Fossey.
Chem. Asian J. 2010, 5, 581-588.
Synthesis of 3-vinyl-2,5-dihydrofuran ring system via enyne metathesis.
S. Vuong, M.M. Rodriguez-Fernandez, B. Renoux, C. Len.
Carbohydr. Res. 2010, 345, 324-329.
2009
Potential supramolecular cyclodextrin dimers using nucleobase-pairs.
F. Hamon, B. Violeau, F. Turpin, M. Bellot, L. Bouteiller, F. Djedaini-Pilard, C. Len.
Synlett 2009, 17, 2875-2879.
Azobenzenes-Synthesis and carbohydrate application.
F. Hamon, F. Djedaini-Pilard, F. Barbot, C. Len.
Tetrahedron 2009, 65, 10105-10123.
Silica-supported Palladium: Sustainable catalysts for cross-coupling reactions.
V. Polshettiwar, C. Len, A. Fihri.
Coord. Chem. Rev. 2009, 253, 2599-2626.
2008
Synthesis and structure of novel cyclonucleoside analogues of uridine.
S. Zhong, M. Mondon, S. Pilard, C. Len.
Tetrahedron 2008, 64, 7828-7836.
Synthesis of cyclonucleosides having a C-C bridge.
C. Len, M. Mondon, J. Lebreton.
Tetrahedron 2008, 64, 7453-7475.
2007
3-Vinyl-2,5-dihydrofuran derivatives via enyne metathesis.
M.M. Rodriguez-Fernandez, S. Vuong, B. Renoux, C. Len.
Synlett 2007, 11, 1703-1706.
2006
Diatereoisomeric synthesis of novel analogues of d4T having an isochroman glycon moiety.
C. Len.
Lett. Org. Chem. 2006, 3, 42-44.
Synthesis of 2',3'-didehydro-2',3'-dideoxynucleosides having variations at either or both of the 2'- and 3'-positions.
C. Len, G. Mackenzie.
Tetrahedron 2006, 62, 9085-9107.
Synthesis of novel dinucleosides via tandem cross metathesis and ring-closing metathesis.
S. Zhong, M. Mondon, S. Pilard, C. Len.
Tetrahedron Lett. 2006, 47, 6221-6224.
Synthesis of 2',3'-cyclohexen bicyclic uridine analogues using ring-closure metathesis.
J. Drone, M. Egorov, W. Hatton, M.-J. Bertrand, C. Len, J. Lebreton.
Synlett 2006, 1339-1342.
Synthesis of 2',3'-didehydro-2',3'-dideoxynucleosides via nucleoside route.
C. Len, D. Postel.
Current Org. Synth. 2006, 3, 261-281.
Enantioseparation of cis and trans nucleosides, aromatic analogues of stavudine, by capillary electrophoresis and high-performance liquid chromatography.
E. Lipka, C. Len, C. Rabiller, J.P. Bonte, C. Vaccher.
J. Chromatogr. A 2006, 1132, 141-147.
2005
Enantiomerical excess determination, puridfication and biological evaluation of (3 S ) and (3 R ) a , b -butenolide analogues of isobenzofuranone.
Lipka, M.P. Vaccher, C. Vaccher, C. Len.
Bioorg. Med. Chem. Lett. 2005, 15, 501-504.
Asymmetric synthesis of thymine nucleoside analogues based on the isochroman core.
C. Len, B. Violeau.
Tetrahedron Lett. 2005, 46, 4835-4838.
First synthesis and evaluation of the inhibitory effects of aza analogues of TSAO on HIV-1 replication.
A. Nguyen Van Nhien, C. Tomassi, C. Len, J.L. Marco-Contelles, J. Balzarini, C. Pannecouque, E. De Clercq, D. Postel.
J. Med. Chem. 2005, 48, 4276-4284.
Synthesis of diastereo-isomeric pairs of novel analogues of d4T having an isochroman glycon moiety ; their enzymatic kinetic resolution, their enantiopure synthesis, molecular modeling and NMR structural study.
C. Len, S. Pilard, E. Lipka, C. Vaccher, M.P. Dubois, Y. Shrinska, V. Tran, C. Rabiller.
Tetrahedron 2005, 61, 10583-10595.
Synthesis, conformation and antiviral activity of nucleoside analogues with the (2-hydroxy-1-phenylethoxy)methyl glycone - a family of nucleoside analogues related to d4T and aciclovir.
D. F. Ewing, V. Glacon, C. Len, G. Mackenzie.
New J. Chem. 2005, 29, 1461-1468.
2004
Synthesis and transformations of [1,2- O -isopropylidene- a -D- erythro (and a - D - ribo )furanose]-3-spiro-3'-(4'-amino-5'H-2',3'-dihydroisothiazole-1,1'-dioxide) derivatives.
A. Nguyen Van Nhien, L. Dominguez, C. Tomassi, M. Rosario Torres, C. Len, D. Postel, J. Marco-Contelles.
Tetrahedron 2004, 60, 4709-4727.
Enantioseparation of four cis and trans diastereoisomers of d4T analogs, by High Performance Liquid Chromaography and Capillary Electrophoresis.
E. Lipka, A. Sélouane, D. Postel, C. Len, M.P. Vaccher, J.P. Bonte, C. Vaccher.
J. Chromatogr. A. 2004, 1034, 161-167.
Synthesis of 4-amino-5- H -dihydroisothiazole-1,1-dioxide ring system on sugar template via carbanion-mediated sulfonamide intramolecular cyclization reactions (CSIC protocols) of glyco-a-sulfonamidonitriles.
L. Dominguez, A. Nguyen Van Nhiem, C. Tomassi, C. Len, D. Postel, J.L. Marco-Contelles.
J. Org. Chem. 2004, 69, 843-856.
Enantioseparation of new nucleoside analogs, related to d4T and acyclovir, by chiral capillary electrophoresis using highly sulfated b -cyclodextrine.
E. Lipka, C. Danel, M.P. Vaccher, V. Glacon, D.F. Ewing, G. Mackenzie, C. Len, J.P. Bonte, C. Vaccher.
Electrophoresis 2004, 25, 444-453.
2003
Electrospray tandem mass spectrometric analysis of diastereo- and stereoisomeric pyrimidine nucleoside analogues based on the 1,3-dihydrobenzo[c]furan core.
C. Len, G. Mackenzie, D.F. Ewing, G. Sheppard, J. Banoub.
Carbohydr. Res. 2003, 338, 2311-2324.
HPLC separation and determination of enantiomeric purity of novel nucleoside analogues, on cyclodextrin chiral stationary phases using reversed and polar organic modes.
E. Lipka, V. Glacon, G. Mackenzie, D.F. Ewing, C. Len, D. Postel, M.P. Vaccher, J.P. Bonte, C. Vaccher.
Anal. Lett. 2003, 37, 385-398.
1,3-Dihydrobenzo[c]furan nucleoside analogues: additional studies of the thymine derivative.
D. Egron, C. Périgaud, G. Gosselin, A.M. Aubertin, A. Faraj, A. Sélouane, D. Postel, C. Len.
Bioorg. Med. Chem. Lett. 2003, 13, 4473-4475.
Synthesis of acyclic bis-vinyl pyrimidines: a general route to d4T via metathesis.
D.F. Ewing, V. Glaçon, G. Mackenzie, D. Postel, C. Len.
Tetrahedron 2003, 59, 941-945.
Asymmetric synthesis of (3 S) 3-benzoyloxymethylisobenzofuranone and its 3 R enantiomer as analogues of a , b -butenolides.
C. Len, A. Sélouane, A. Weiling, F. Coicou, D. Postel.
Tetrahedron Lett. 2003, 44, 663-666.
On the origin of the facial selectivity of the Sharpless Asymmetric Dihydroxylation of styrene derivatives.
N. Moitessier, C. Henry, C. Len, D. Postel, Y. Chapleur.
J. Carbohydr. Chem. 2003, 22, 25-34.
Synthesis, stability and biological evaluation of 1,3-dihydrobenzo[c]furan analogues of d4T and its SATE pronucleotide.
C. Len, A. Sélouane, D. Postel, P. Villa, A.M. Aubertin, D. Egron, G. Gosselin, C. Périgaud.
Nucleos. Nucleot. Nucleic Acids 2003, 5-8, 943-946.
Synthesis of aza analogues of TSAO.
A. Nguyen Van Nhiem, C. Tomassi, C. Len, J.L. Marco-Contelles, D. Postel.
Nucleos. Nucleot. Nucleic Acids 2003, 5-8, 939-942.
2002
Chiral separation of enantiomeric purity of nucleoside analogs to d4T and acyclovir by liquid chromatography, on amylose chiral stationary phases and determination of enantiomeric purity.
E. Lipka-Belloli, V. Glaçon, G. Mackenzie, D. Ewing, C. Len, C. Vaccher, J.P. Bonte.
Chromatographia 2002, 56, 567-572.
Determination of enantiomeric purity of nucleoside analogs, related to d4T and acyclovir new potential antiviral agents, using HPLC on cellulose chiral stationary phases.
E. Lipka-Belloli, V. Glaçon, G. Mackenzie, D. Ewing, C. Len, C. Vaccher, J.P. Bonte.
J. Chromatogr. A. 2002, 972, 211-219.
Towards a computational tool predicting the stereochemical outcome of asymmetric reactions. 1. Application to Sharpless asymmetric dihydroxylation.
N. Moitessier, C. Henry, C. Len, Y. Chapleur.
J. Org. Chem. 2002, 67, 7275-7282.
Novel conformationally restricted glycoamino acids from glyco-a-aminonitrile as potent turn mimics in peptide synthesis.
A. Nguyen Van Nhien, H. Ducatel, C. Len, D. Postel.
Tetrahedron Lett. 2002, 43, 3805-3808.
A novel approach to unsaturated acyclic nucleoside analogues and the first synthesis of d4T by ring closure metathesis.
D. Ewing, V. Glaçon, G. Mackenzie, D. Postel, C. Len.
Tetrahedron Lett. 2002, 43, 3503-3505.
Asymmetric dihydroxylation of chiral styrene derivatives: development of an analytical strategy for the determination of the diastereomeric excess.
S. Pilard, D. Riboul, V. Glaçon, N. Moitessier, Y. Chapleur, D. Postel, C. Len.
Tetrahedron: Asymmetry 2002, 13, 529-537.
Enantiomeric d4T analogues and their structural determination.
A. Selouane, C. Vaccher, P. Villa, D. Postel, C. Len.
Tetrahedron: Asymmetry 2002, 13, 407-413.
Asymmetric synthesis of both enantiomers of two acyclic nucleoside analogues related to d4T and acyclovir.
D. Ewing, V. Glaçon, G. Mackenzie, C. Len.
Tetrahedron Lett. 2002, 43, 989-991.
Acyclic nucleoside analogues related to d4T and Acyclovir - Synthesis and conformation.
D.F. Ewing, V. Glaçon, G. Mackenzie, D. Postel, C. Len.
Collection Symposium Series (Z. Tocik and M. Hocek, Eds) 2002, 5, 261-266.
A novel class of unsaturated acyclic nucleosides and the first synthesis of d4T by ring closure metathesis.
V. Glaçon, D.F. Ewing, G. Mackenzie, D. Postel, C. Len.
Collection Symposium Series (Z. Tocik and M. Hocek, Eds) 2002, 5, 316-318.
2001
Diastereomeric resolution of nucleoside analogues, new potential antiviral agents, using high-performance liquid chromatography on polysaccharide-type chiral stationary phases.
E. Belloli, C. Len, G. Mackenzie, G. Ronco, J.P. Bonte, C. Vaccher.
J. Chromatogr. A 2001, 943, 91-100.
Asymmetric synthesis of aromatic azasaccharide: new potent inhibitors of glycosidases and reverse transcriptase of HIV.
D.F. Ewing, C. Len, G. Mackenzie, J.P. Petit, G. Ronco, P. Villa.
J. Pharm. Pharmacol. 2001, 53, 945-948.
Synthesis of poly(dithio-, thio- and carbamoyl (thio)ester) derivatives of D-glucose.
C. Len, D. Postel, B. Meddah, P. Villa, G. Ronco.
Phosphorus Sulfur Silicon 2001, 173, 59-65.
2000
Asymmetric synthesis of 1,3-dihydrobenzo[ c ]furan derivatives using a D-xylose moiety as a chiral auxiliary.
D.F. Ewing, C. Len, G. Mackenzie, G. Ronco, P. Villa.
Tetrahedron: Asymmetry 2000, 11, 4995-5002.
Stereoisomeric pyrimidine nucleoside analogues based on the benzo[c]furane core.
D.F. Ewing, N. Fahmi, C. Len, G. Mackenzie, A. Pranzo.
J. Chem. Soc., Perkin Trans. 1 2000, 21, 3561-3565.
Synthesis and antifungal activity of novel bisdithiocarbamate derivatives of carbohydrates against Fusarium oxysporum f. sp. Lini.
C. Rafin, E. Veignie, M. Sancholle, D. Postel, C. Len, P. Villa, G. Ronco.
J. Agric. Food Chem. 2000, 48, 5283-5287.
1999
Nucleoside analogues with a novel glycone based on the benzo[c]furan core.
D.F. Ewing, N. Fahmi, C. Len, G. Mackenzie, G. Ronco, P. Villa, G. Shaw.
Nucleosides Nucleotides 1999, 18, 2613-2630.
Strategy for the preparation of 2' and 3' branched nucleosides.
C. Len, D. Postel, G. Mackenzie, P. Villa, G. Ronco.
Pharm. Pharmacol. Commun. 1999, 5, 165-168.
1998
Synthesis of dithio-, thio- and carbamoyl ester derivatives of monosaccharides and itols.
C. Len, D. Postel, G. Ronco, P. Villa.
Phosphorus Sulfur Silicon 1998, 133, 41-59.
1997
Synthesis of carbamic esters derivatives of itols: antifungal activity against various crop diseases.
C. Len, D. Postel, G. Ronco, P. Villa, C. Goubert, E. Jeufrault, B. Mathon, H. Simon.
J. Agric. Food Chem. 1997, 45, 3-6.
Synthesis of bis(carbamoyl ester) derivatives of D-glucose as antifungal products.
C. Len, D. Postel, G. Ronco, P. Villa.
J. Carbohydr. Chem. 1997, 16, 1029-1049.
1996
Nucleoside analogues: glycones based on the benzo[c]furan core.
D.F. Ewing, N. Fahmi, C. Len, G. Mackenzie, G. Ronco, P. Villa, G. Shaw.
Collect. Czech. Chem. Commun. 1996, 61, 145-147.
Synthesis and antifungal activity of novel bis(dithiocarbamate) derivatives of glycerol.
C. Len, A.S. Merlot, D. Postel, G. Ronco, P. Villa, C. Goubert, E. Jeufrault, B. Mathon, H. Simon.
J. Agric. Food Chem. 1996, 44, 2856-2858.
